Absolute application of the DPI inequality to assess the direct interaction structure of a three node sub-network. Panel A depicts a three node subnetwork composed by nodes α, β and γ. Interactions were inferred by means of mutual information calculations for a selected quantitative feature. The interaction strength between the nodes i, j is given by the respective MI
(i, j = α, β, γ) values. Panels B, C, and D result from pruning the subnetwork from the link with the lowest MI
: MIα, β (B), MIβ, γ (C), and MIα, γ (D).